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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNRF1 All Species: 13.33
Human Site: Y103 Identified Species: 26.67
UniProt: Q8ND25 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8ND25 NP_115644.1 227 23783 Y103 T Y A H G N G Y Q E T G G G H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001109563 278 29893 Y103 T Y A H G N G Y Q E T G G S H
Dog Lupus familis XP_854366 187 20677 D66 S L Y L Y L F D Q K P Q S A R
Cat Felis silvestris
Mouse Mus musculus Q91V17 227 23824 Y103 T Y A H G N G Y Q E T G G G H
Rat Rattus norvegicus XP_002725463 227 23854 Y103 T Y A H G N G Y Q E T G G G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512110 89 10164
Chicken Gallus gallus XP_418778 146 15603 P25 Q D S V S S T P E E G G R D R
Frog Xenopus laevis Q66KG7 195 20714 R73 R A G P D T E R G G G S G S E
Zebra Danio Brachydanio rerio Q6P4U6 215 22857 G95 G N G Y Q E T G G G H H T D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572359 303 31946 M179 D S I R D M S M T G G S I A E
Honey Bee Apis mellifera XP_624991 212 22738 G92 S S V G V G V G Q A L G L P Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198564 213 21441 P93 S R G P D S D P S S S E N S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 80.9 44.9 N.A. 99.1 98.6 N.A. 31.2 44.4 72.2 82.8 N.A. 37.6 38.7 N.A. 39.2
Protein Similarity: 100 N.A. 80.9 55.9 N.A. 99.1 98.6 N.A. 35.6 53.7 77.9 88.1 N.A. 47.1 50.2 N.A. 52.8
P-Site Identity: 100 N.A. 93.3 6.6 N.A. 100 100 N.A. 0 13.3 6.6 0 N.A. 0 13.3 N.A. 0
P-Site Similarity: 100 N.A. 93.3 20 N.A. 100 100 N.A. 0 33.3 6.6 6.6 N.A. 0 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 34 0 0 0 0 0 0 9 0 0 0 17 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 0 25 0 9 9 0 0 0 0 0 17 0 % D
% Glu: 0 0 0 0 0 9 9 0 9 42 0 9 0 0 17 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 25 9 34 9 34 17 17 25 25 50 42 25 9 % G
% His: 0 0 0 34 0 0 0 0 0 0 9 9 0 0 34 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % K
% Leu: 0 9 0 9 0 9 0 0 0 0 9 0 9 0 0 % L
% Met: 0 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 34 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 17 0 0 0 17 0 0 9 0 0 9 0 % P
% Gln: 9 0 0 0 9 0 0 0 50 0 0 9 0 0 9 % Q
% Arg: 9 9 0 9 0 0 0 9 0 0 0 0 9 0 17 % R
% Ser: 25 17 9 0 9 17 9 0 9 9 9 17 9 25 0 % S
% Thr: 34 0 0 0 0 9 17 0 9 0 34 0 9 0 0 % T
% Val: 0 0 9 9 9 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 34 9 9 9 0 0 34 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _